Oxidative Folding of Peptides and Proteins

212,00€

Osnovne informacije

GLS Croatia
Besplatna dostava za narudžbe iznad 50€
Rok dostave: 10-15 dana
3.50€ 26kn

Plaćanje karticama - CorvusPay
sigurno i pouzdano plaćanje karticama
Bankovna transakcija
općom uplatnicom / virmanom / internet bankarstvom / qr kod
KeksPay

Sažetak

Description The formation of disulfide bonds is probably the most influential modification of peptides and proteins. An elaborate set of cellular machinery exists to catalyze and guide this process. In recent years, significant developments have been made in both our understanding of the in vivo situation and the in vitro manipulation of disulfide bonds. This is the first monograph to provide a comprehensive overview of this exciting and rapidly developing area. It offers in-depth insights into the mechanisms of in vivo and in vitro oxidative folding of proteins as well as mono- and multiple-stranded peptides. Procedures applied for laboratory and industrial purposes are also discussed by top experts in the field. The book describes the enzymes involved in the correct oxidative folding of cysteine-containing proteins in prokaryotes and eukaryotes. It then goes on to discuss the mimicking of these enzymes for successful in vitro folding of proteins (including synthetic replicates) and to deal with important issues concerning cysteine-rich peptides. The ability of natural bioactive peptides to fold correctly, and in high yields, to form defined structural motifs using cysteine sequence patterns is still puzzling. With this in mind, synthetic procedures for establishing native cysteine frameworks are discussed using selected examples, such as the potential of selenocysteines. The biotechnological and pharmaceutical relevance of proteins, peptides, their variants and synthetic replicates is continuously increasing. Consequently, this book is invaluable for peptide and protein chemists involved in related research and production.

Dodatne informacije

0 Recenzije

0.00 Prosječna ocjena
5
0
4
0
3
0
2
0
1
0

Trenutno nema ocjena i komentara za ovaj artikl!

Napišite recenziju

Molimo unesite vaše ime!
Molimo upišite ispravnu email adresu!
Molimo odaberite ocjenu!
Molimo napišite recenziju!

POVEZANI PROIZVODI

Top